Available at http://ebooks.benthamscience.com/book/9781681084596/
Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms
Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability.
This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacy and pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.
CONTENTS:
FOREWORD by Sanjay Garg
Professor of Pharmaceutical Science, School of Pharmacy and Medical Sciences, University of South Australia,City East Campus, Adelaide, SA, Australia
CHAPTERS:
1. FAST DISSOLVING/DISINTEGRATING DOSAGE FORMS: INTRODUCING THROUGH DEVELOPMENT, MARKET, PHARMACOPOEIAL AND REGULATORY STATUS by Vikas A. Saharan, Anupama Singh and Vandana Kharb
2. FREEZE DRYING TECHNOLOGIES FOR DEVELOPING FAST DISSOLVING/DISINTEGRATING TABLETS by Vikas A. Saharan
3. MODIFICATIONS IN CONVENTIONAL TABLET COMPACTION TECHNOLOGIES FOR DEVELOPING FAST DISSOLVING/ DISINTEGRATING TABLETS by Vikas A.Saharan
4. MOULDING, EXTRUSION, FLOSS AND THREE DIMENSIONAL PRINTING TECHNOLOGIES FOR DEVELOPING FAST DISSOLVING/DISINTEGRATING TABLETS by Vikas A. Saharan
5. PATENT INNOVATIONS IN FAST DISSOLVING/ DISINTEGRATING DOSAGE FORMS by Kalpana Nagpal, Shailendra K. Singh and D. N. Mishra
6. EXCIPIENTS FOR FAST DISSOLVING /DISINTEGRATING TABLETS by Vikas A. Saharan
7. TASTE MASKING IN FAST DISSOLVING/DISINTEGRATING DOSAGE FORMS by Vikas A. Saharan, Vandana Kharb and Anupama Singh
8. QUALITY ASSURANCE AND EVALUATION OF FAST DISSOLVING/DISINTEGRATING DOSAGE FORMS by Vikas A. Saharan
9. CLINICAL STUDIES ON FAST DISSOLVING/DISINTEGRATING DOSAGE FORMS Prashant Mathur, Arita Jindal, Sokindra Kumar and Vikas Anand Saharan
10. FAST DISSOLVING ORAL FILMS by Mahaveer Singh and Hemant R. Jadhav
11. NOVEL FAST DISSOLVING/DISINTEGRATING DOSAGE FORMS Vikas A. Saharan
12. APPROVED AND MARKETED FAST DISSOLVING/ DISINTEGRATING DRUG PRODUCTS Vikas A. Saharan, Anupama Singh and Vandana Kharb
Saturday, May 27, 2017
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Thanks for sharing this greate article...
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disintegrating critical infrastructure
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